Fungal spores spend the winter on twigs and buds before germinating in the spring. Preventative applications of a fungicide can be made after leaves have fallen and before bud swell, typically between late November and February depending on your location in California. Spraying a fungicide during the growing season when you observe symptoms of peach leaf curl is not effective.
Always be sure to follow pesticide label directions for the correct coverage, mixing rate, and disposal. Prepare for the treatment by having the right pesticide application equipment (measuring cups just for pesticides, spray gear, etc.) and protect yourself by wearing the proper personal protection equipment.
For more information, see our Pest Notes: Peach Leaf Curl and Pesticides: Safe and Effective Use in the Home and Landscape.
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